
C-Spor 0.05% Eyes Drops, 10ml - Ophth Pharma
Cyclosporin, the active ingredient in Cyclosporin Drops, primarily exerts its immunosuppressive effect by forming a complex with cyclophilin, a cytosolic protein found in T-lymphocytes. This drug-protein complex inhibits calcineurin, a calcium-dependent...
Cyclosporin, the active ingredient in Cyclosporin Drops, primarily exerts its immunosuppressive effect by forming a complex with cyclophilin, a cytosolic protein found in T-lymphocytes. This drug-protein complex inhibits calcineurin, a calcium-dependent phosphatase enzyme. By blocking calcineurin, cyclosporin prevents the dephosphorylation and nuclear translocation of the nuclear factor of activated T cells (NF-AT), which is essential for the transcription of specific cytokine genes, such as interleukin-2 (IL-2). This inhibition suppresses T-cell activation and proliferation, thereby reducing the immune response in the targeted area.
Composition
Each ml contains:
- Cyclosporine: 0.5% mg
Suggested Usage
- Use as per physician's advice.
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