Sevelamer HCI is a non-absorbable polymeric amine and phosphate binding agent that can be used to prevent hyperphosphatemia. Upon oral administration, the amine group in sevelamer becomes protonated in the intestine and binds to the dietary phosphate group in the gastrointestinal (GI) tract, thereby preventing the absorption of phosphate and controlling phosphate plasma levels. In addition, sevelamer, as a phosphate binder, can be used to prevent the absorption of radionuclide phosphorus.
Composition
Each film coated tablet contains:
- Sevelamer HCI: 400 mg
Dosage
- As directed by the physician.
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